Paraneoplastic cerebellar degeneration (PCD)

Paraneoplastic cerebellar degeneration (PCD)

(PCD) is a rare neurological disorder characterized by a widespread loss of Purkinje cells associated with a progressive pancerebellar dysfunction

Paraneoplastic cerebellar degeneration (PCD) is a rare neurological disorder characterized by a widespread loss of Purkinje cells associated with a progressive pancerebellar dysfunction. Paraneoplastic syndromes are a group of rare disorders that are triggered by an abnormal immune system response to an underlying (usually undetected) malignant tumor. Patients with paraneoplastic neurological syndrome (PNS) most often present with neurologic symptoms before an underlying tumor is detected.
Paraneoplastic neurologic syndromes include many neurologic disorders including paraneoplastic cerebellar degeneration (PCD) caused by an immune-mediated mechanism other than a metastatic complication in patients with an underlying malignancy. Any part of the nervous system can be involved depending on the type of primary malignancy.

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Patricia Barber
Patricia Barber
For the last 20 years, Pat has been helping patients and caregivers live better lives, advocate for change, and Virginia's "right hand" making sure the "i's" are dotted and the "t's" are crossed. She lives in Michigan and couldn't picture herself doing anything but helping the autoimmune community.

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